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The two MEPH and nor-MEPH were detected in all substrates, with the highest levels detected in lungs. Mean brain: serum ratios had been one:one.19 (MEPH) and 1:one.91 (nor-MEPH), utmost concentrations ended up noticed at thirty min; at 2 and four h immediately after administration, nor-MEPH concentrations were larger when compared with the dad or m